INVESTIGADORES
ALTCHEH Jaime Marcelo
artículos
Título:
Molecular diagnosis and treatment monitoring of congenital transmission of Trypanosoma cruzi to twins of a triplet delivery
Autor/es:
BURGOS JM; ALTCHEH J; PETRUCELLI N; BISIO M; LEVIN M; FREILIJ H; SCHIJMAN AG
Revista:
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASES
Editorial:
ELSEVIER SCIENCE INC
Referencias:
Lugar: Amsterdam; Año: 2009 p. 58 - 61
ISSN:
0732-8893
Resumen:
Congenital transmission of Trypanosoma cruzi was diagnosed in 2 triplets born to a triamniotic bichorionic delivery. Only the sisters sharing the placenta became infected, as diagnosed by microhematocrit and/or polymerase chain reaction of 3 parasite targets. The neonates´ parasitologic response to benznidazole was monitored. Molecular strategies allowed genotyping lineage IId and identical minicircle signatures in both triplets, showing they harbored the same maternal parasite populations.
