INVESTIGADORES
DIAZ Luis Adrian
artículos
Título:
Eco-epidemiología del virus encefalitis st. Louis en Córdoba, Argentina.
Autor/es:
LORENA I. SPINSANTI; LUIS A. DIAZ; MARTA S. CONTIGIANI
Revista:
Revista de la Facultad de Ciencias Médicas (Córdoba, Argentina)
Editorial:
Facultad de Ciencias Médicas, Universidad Nacional de Córdoba
Referencias:
Lugar: Córdoba, Argentina; Año: 2009 vol. 66 p. 52 - 59
ISSN:
0014-6722
Resumen:
St. Louis encephalitis virus (SLEV) belongs
to
Flavivirus genus, Flaviviridae family. It is endemic in the
American continent. Most of infections by SLEV are
asymptomatic, however clinical outcome include encephalitis,
aseptic meningitis and febrile cephalea. The susceptibility
to acquired neurological infection increase with age. In the
USA, SLEV is maintaining through Culex spp mosquitoes and
passeriformes and columbiformes birds species. In Argentina,
viral strains has been isolated from humans and mosquitoes
(virulent
strains) and from rodents (attenuated strains). Serological
surveillance carried out in Cordoba city indicate an endemic
and extended activity of SLEV. In contrast to the USA,
encephalitis outbreak by SLEV are uncommon in the rest of
the continent. However, an unexpected outbreak occurred in
Cordoba province during summer-fall of 2005. Overall, 49
symptomatic cases were reported and two viral strains were
isolated from Culex quinquefasciatus mosquitoes. Ecological
studies allowed us to identify the main urban and periurban
mosquito vector (Culex quinquefasciatus) and avian hosts (Eared
doves and Picui ground dove) for SLEV in Córdoba. Our
results pointed out that introduction of a new more
viremogenic genotype and a high proportion of susceptible
birds host availability previous the outbreak would be some
of the causes for the SLEV re emergence in Córdoba.