INVESTIGADORES
TODARO Laura Beatriz
artículos
Título:
Alteration of serum and tumoral neural cell adhesion molecule
Autor/es:
LAURA TODARO; SILVIA CHRISTIANSEN; MIRTA VARELA; PAOLA CAMPODO´ NICO; M. GUADALUPE PALLOTTA; JOSE´ LASTIRI; EUGENIA SACERDOTE DE LUSTIG; ELISA BAL DE KIER JOFFE; LYDIA PURICELLI
Revista:
JOURNAL OF NEURO-ONCOLOGY.
Editorial:
Kluwer Academic
Referencias:
Lugar: Londres; Año: 2007 vol. 83 p. 135 - 144
ISSN:
0167-594X
Resumen:
Abstract The neural cell adhesion molecule (NCAM) is involved in the intercellular junctions of neurons and glial cells. We investigated its relevance as a biomarker in gliomas which main characteristic is their high invasiveness.We studied by Western blot the pattern of serum NCAM bands in patients with gliomas (n = 34), with brain metastasis of different primary cancers (n = 27) and with benign brain tumors (n = 22)] compared with healthy controls (n = 69). For densitometric analysis NCAM bands 130 kDa (HMW) and
