INVESTIGADORES
KAUFMAN Teodoro Saul
artículos
Título:
Total Synthesis of Waltherione F, a Nonrutaceous 3-Methoxy-4-quinolone, Isolated from Waltheria indica L. F.
Autor/es:
ARROYO AGUILAR, ABEL A.; BOLÍVAR AVILA, SANTIAGO J.; KAUFMAN, TEODORO S.; LARGHI, ENRIQUE L.
Revista:
ORGANIC LETTERS
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2018 vol. 20 p. 5058 - 5061
ISSN:
1523-7060
Resumen:
Waltherione F was totally synthesized in seven steps and 31% overall yield from 2-nitro-3-methylanisole without the use of protecting groups. Key steps in the sequence were a Suzuki−Miyaura coupling to attach the n-octyl chain and a microwave-promoted cyclization of an acetonyl anthranilate to give the heterocyclic core whose 3-OH was O-methylated
