INVESTIGADORES
IRIBARREN Adolfo Marcelo
artículos
Título:
Complete and regioselective deacetylation of peracetylated uridines using a lipase
Autor/es:
L. IGLESIAS; M.A.ZINNI; M. GALLO; A IRIBARREN
Revista:
BIOTECHNOLOGY LETTERS
Editorial:
SPRINGER
Referencias:
Lugar: Berlin; Año: 2000 p. 361 - 365
ISSN:
0141-5492
Resumen:
Lipase-catalysed alcoholysis and hydrolysis of 20,30,50-tri-O-acetyluridine (1a)and20,30,50-tri-O-acetyl-20-Cmethyluridine (1b) were studied. Conditions for full and regioselective deacetylation of 1aand1bare shown in the present work. New compound 20,30-di-O-acetyl-20-C-methyluridine (3b) was prepared by regioselectivelipase-catalysed deacetylation