Activated carbons as potentially useful nonnutritive additives to prevent the effect of fumonisin B1 on the sodium bentonite activity against chronic aflatoxicosis

M.P. MONGE; A.P. MAGNOLI; M.V. BERGESIO; N. TANCREDI; C.E. MAGNOLI; S.M. CHIACCHIERA

FOOD ADDITIVES AND CONTAMINANTS

TAYLOR & FRANCIS LTD

Lugar: Londres; Año: 2016

0265-203X

Aflatoxin B1 (AFB1) and Fumonisin B1 (FB1) are mycotoxins that often co-occur infeedstuffs. The ingestion of AFB1 causes aflatoxicosis in humans and animals. Sodium bentonite(NaB), a cheap non-nutritive unselective sequestering agent incorporated in animal diets, caneffectively prevent aflatoxicosis. Fumonisins are responsible for equine leukoencephalomalaciaand porcine pulmonary oedema, and often have subclinical toxic effects in poultries. FumonisinB1 and aflatoxin B1 are both strongly adsorbed in vitro on sodium bentonite. Co-adsorptionstudies, carried out with a weight ratio FB1 to AFB1 that mimics the natural occurrence (200:1),showed that FB1 greatly decreases the in vitro ability of NaB to adsorb AFB1. The ability of twoactivated carbons (AC) to adsorb FB1 was also investigated. Both carbons showed high affinityfor FB1. A complex behaviour of the FB1 adsorption isotherms with pH was observed. In vitroresults suggest that under natural contamination levels of AFB1 and FB1, a mixture of activatedcarbon and sodium bentonite might be potentially useful for prevention of sub-acuteaflatoxicosis.