Existence and coexistence of calcitonin gene-related peptide-, vasoactive intestinal polypeptide- and somatostatin-like immunoreactivities in spinal cord motoneurons of developing embryos and post-hatch chicks.

VILLAR, M.J., M. HUCHET, T. HÖKFELT, J. P. CHANGEUX, J. FAHRENKRUG AND J. C. BROWN.

NEUROSCIENCE LETTERS

ELSEVIER IRELAND LTD

Lugar: Amsterdam; Año: 1988 vol. 86 p. 114 - 118

0304-3940

Abstract By use of immunocytochemical methods, it is shown that immunoreactive calcitonin gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP) and somatostatin (SOM) are present in motoneurons in the chicken spinal cord. While CGRP-like immunoreactivity (LI) is present in numerous motoneurons both before and after hatching, SOM- and VIP-LI markedly decline at the end of the embryonic period. Evidence is also provided for coexistence of some of these peptides in certain spinal motoneurons. PMID: 3258975 [PubMed - indexed for MEDLINE]