INVESTIGADORES
GOMEZ CASATI Diego Fabian
artículos
Título:
Carbonic Anhydrase subunits physically interact within complex I of plant mitochondria
Autor/es:
PERALES, M.; PARISI, G.; FORNASARI, M. S.; COLANERI, A.; VILLARREAL, F.; ECHAVE, J.; DIEGO FABIAN GOMEZ CASATI; BRAUN, H. P.; ARAYA, A.; EDUARDO ZABALETA
Revista:
PLANT MOLECULAR BIOLOGY
Editorial:
Springer
Referencias:
Año: 2004 vol. 56 p. 947 - 957
ISSN:
0167-4412
Resumen:
We report the identification by two hybrid screens of two novel similar proteins, called Arabidopsis thalianaArabidopsis thaliana
gamma carbonic anhydrase like1 and 2 (AtcCAL1 and AtcCAL2), that interact specifically with putativecCAL1 and AtcCAL2), that interact specifically with putative
Arabidopsis thaliana gamma Carbonic Anhydrase (AtcCA) proteins in plant mitochondria. The interaction
region that was located in the N-terminal 150 amino acids of mature AtcCA and AtcCA like proteins
represents a new interaction domain. In vitro experiments indicate that these proteins are imported into
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
represents a new interaction domain. In vitro experiments indicate that these proteins are imported into
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
region that was located in the N-terminal 150 amino acids of mature AtcCA and AtcCA like proteins
represents a new interaction domain. In vitro experiments indicate that these proteins are imported into
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
represents a new interaction domain. In vitro experiments indicate that these proteins are imported into
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
mitochondria and are associated with mitochondrial complex I as AtcCAs. All plant species analyzed
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
contain both AtcCA and AtcCAL sequences indicating that these genes were conserved throughout plant
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
residues with respect to cCAs but could form active interfaces in the interaction with AtcCAs.We postulate
a CA complex tightly associated to plant mitochondrial complex
a CA complex tightly associated to plant mitochondrial complex
evolution. Structural modeling of AtcCAL sequences show a deviation of functionally important active site
residues with respect to