INVESTIGADORES
MOGLIONI Albertina Gladys
artículos
Título:
Stereodivergent and efficient synthesis of the first bis(cyclobutane) g-dipeptides
Autor/es:
AGUILERA J., MOGLIONI A., MOLTRASIO G. AND ORTUÑO R
Revista:
TETRAHEDRON-ASYMMETRY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2008 vol. 8 p. 302 - 308
ISSN:
0957-4166
Resumen:
Diastereomeric bis(cyclobutane) c-dipeptides, a new class of c-peptides, have been synthesized efficiently from both enantiomers of conveniently protected 3-amino-2,2-dimethyl-1-carboxylic acid. These amino acids have been prepared in very good overall yields through enantiodivergent synthetic routes starting from (-)-cis-pinononic acid. Mixed c-oligomers have also been prepared from GABA and cyclobutane residues.
