INVESTIGADORES
MOGLIONI Albertina Gladys
artículos
Título:
Stereoselective synthesis of chiral precursors of cyclobutane carboxyclic nucleosides and oligopeptides
Autor/es:
P. ROUGE, A. MOGLIONI, G. MOLTRASIO AND R. M. ORTUÑO
Revista:
TETRAHEDRON-ASYMMETRY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2003 vol. 14 p. 193 - 195
ISSN:
0957-4166
Resumen:
Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, -amino acids and -amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (−)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium.
