INVESTIGADORES
PONCE DAWSON Silvina Martha
artículos
Título:
The fire-diffuse-fire model of Calcium dynamics
Autor/es:
SILVINA PONCE DAWSON; JOEL E. KEIZER; JOHN E. PEARSON
Revista:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Referencias:
Año: 1999 vol. 96 p. 6060 - 6063
ISSN:
0027-8424
Resumen:
When Ca2+ is released from internal stores in living cells, the resulting wave of increased concentration can travel without deformation (continuous propagation) or with burst-like behavior (saltatory propagation). We analyze the "fire-diffuse-fire" model in order to illuminate the differences between these two modes of propagation. We show that the Ca2+ release wave in immature Xenopus oocytes and cardiac myocytes is saltatory, whereas the fertilization wave in the mature oocyte is continuous.