Different susceptibility of two aquatic vertebrates (Oncorhynchus mykiss and Bufo arenarum) to azinphos methyl and carbaryl

FERRARI A; ANGUIANO O.L; SOLEÑO J; VENTURINO A; PECHEN DE D'ANGELO A.M

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. TOXICOLOGY & PHARMACOLOGY

Elsevier

Año: 2004 vol. 139 p. 239 - 243

1532-0456

We studied the effect of two insecticides azinphos methyl and carbaryl on two resident aquatic species (Oncorhynchus mykiss and Bufo arenarum). Juvenile trout and larval stages of toad were used for exposure and recovery assays. O. mykiss was more sensitive to azinphos methyl exposure than B. arenarum larvae, with a mean 96-h LC50 of 0.007 mg/l. Carbaryl is markedly less toxic than the organophosphate and the differences in potency, expressed as LC50, for both species varies only by five-fold. The relationship between cholinesterase (ChE) inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. and the differences in potency, expressed as LC50, for both species varies only by five-fold. The relationship between cholinesterase (ChE) inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. methyl exposure than B. arenarum larvae, with a mean 96-h LC50 of 0.007 mg/l. Carbaryl is markedly less toxic than the organophosphate and the differences in potency, expressed as LC50, for both species varies only by five-fold. The relationship between cholinesterase (ChE) inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. and the differences in potency, expressed as LC50, for both species varies only by five-fold. The relationship between cholinesterase (ChE) inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum). Juvenile trout and larval stages of toad were used for exposure and recovery assays. O. mykiss was more sensitive to azinphos methyl exposure than B. arenarum larvae, with a mean 96-h LC50 of 0.007 mg/l. Carbaryl is markedly less toxic than the organophosphate and the differences in potency, expressed as LC50, for both species varies only by five-fold. The relationship between cholinesterase (ChE) inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. inhibition and lethality is not straightforward: O. mykiss survives with an almost complete inhibition of the brain enzyme when exposed to azinphos methyl and carbaryl. Their IC50 values are one or two orders of magnitude lower than the corresponding 96-h LC50 value. In B. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. courses of enzyme inhibition and recovery also points out differences between both types of pesticides and species. Identifying the key features conferring species selectivity can be exploited to minimize the incidence and severity of intoxication of non-target organism. The data presented here highlight the necessity of including several species and endpoint analyses in the pesticide risk evaluations of aquatic ecosystems. arenarum larvae, the IC50 values for azinphos methyl and carbaryl are one half and one third of their 96-h LC50s, respectively. The time courses of enzyme inhibition and recovery also points out differences between both types