PERSONAL DE APOYO
NOLI TRUANT Sofia
artículos
Título:
Galectin-3 is essential for early wound healing and ventricular remodeling after myocardial infarction in mice.
Autor/es:
GERMÁN E. GONZALEZ; PABLO CASSAGLIA; SOFÍA NOLI TRUANT; MARISA M. FERNANDEZ; LUCIANA WILENSKY; VERÓNICA VOLBERG; EMILIO L. MALCHIODI; CELINA MORALES; RICARDO J. GELPI
Revista:
INTERNATIONAL JOURNAL OF CARDIOLOGY
Editorial:
ELSEVIER IRELAND LTD
Referencias:
Lugar: Amsterdam; Año: 2014 vol. 176 p. 1423 - 1425
ISSN:
0167-5273
Resumen:
Healing after myocardial infarction (MI) is a well-orchestrated time-dependent process that involves inflammation, tissue repair with progressive extracellular collagen matrix (ECM) deposition and scar formation. This scar should provide adequate tensile strength to prevent expansion, subsequent ventricular dilation [1], adverse ventricular remodeling (VR) and dysfunction [2]. Conversely, a defect in the healing process or an increase in the infarct size and parietal stress are major determinants to enhance the expansion and risk of adverse clinical outcomes, failure and death.
