INVESTIGADORES
SAMBUCETTI Pablo Daniel
artículos
Título:
Effects of dietary composition on life span of Drosophila buzzatii and its short-lived sibling species D. koepferae
Autor/es:
F.H. GOMEZ; P SAMBUCETTI; FM NORRY
Revista:
BIOGERONTOLOGY
Editorial:
SPRINGER
Referencias:
Lugar: Berlin; Año: 2013 vol. 14 p. 423 - 429
ISSN:
1389-5729
Resumen:
Two sibling Drosophila species dramatically
divergent in longevity, Drosophila buzzatii andDrosophila species dramatically
divergent in longevity, Drosophila buzzatii andDrosophila buzzatii and
D. koepferae, were examined for possible effects of
both developmental culture medium and dietary
composition (DC) on longevity. Longevity was
greatly increased in the longer lived D. buzzatii when
flies were reared and fed on a rich-in-nutrient and
cactus-based culture (R-CBC) as compared to longevity
in a poor nutrient culture (PNC). In D. buzzatii,
life span was further increased by exposing flies to
short periods of a poor-in-nutrient and cactus-based
culture (P-CBC). In contrast, variation in the here used
nutrient composition did not change life span in the
shorter lived D. koepferae, as longevity in this species
did not differ among R-CBC, P-CBC and PNC
cultures. Hormesis is a plausible explanation for the
beneficial biological effects against aging arising
from brief exposure to a lowed calorie food source
in D. buzzatii. This study shows that genetic variation
between closely related species is substantial for
dietary effects on longevity., were examined for possible effects of
both developmental culture medium and dietary
composition (DC) on longevity. Longevity was
greatly increased in the longer lived D. buzzatii when
flies were reared and fed on a rich-in-nutrient and
cactus-based culture (R-CBC) as compared to longevity
in a poor nutrient culture (PNC). In D. buzzatii,
life span was further increased by exposing flies to
short periods of a poor-in-nutrient and cactus-based
culture (P-CBC). In contrast, variation in the here used
nutrient composition did not change life span in the
shorter lived D. koepferae, as longevity in this species
did not differ among R-CBC, P-CBC and PNC
cultures. Hormesis is a plausible explanation for the
beneficial biological effects against aging arising
from brief exposure to a lowed calorie food source
in D. buzzatii. This study shows that genetic variation
between closely related species is substantial for
dietary effects on longevity.D. buzzatii when
flies were reared and fed on a rich-in-nutrient and
cactus-based culture (R-CBC) as compared to longevity
in a poor nutrient culture (PNC). In D. buzzatii,
life span was further increased by exposing flies to
short periods of a poor-in-nutrient and cactus-based
culture (P-CBC). In contrast, variation in the here used
nutrient composition did not change life span in the
shorter lived D. koepferae, as longevity in this species
did not differ among R-CBC, P-CBC and PNC
cultures. Hormesis is a plausible explanation for the
beneficial biological effects against aging arising
from brief exposure to a lowed calorie food source
in D. buzzatii. This study shows that genetic variation
between closely related species is substantial for
dietary effects on longevity.D. buzzatii,
life span was further increased by exposing flies to
short periods of a poor-in-nutrient and cactus-based
culture (P-CBC). In contrast, variation in the here used
nutrient composition did not change life span in the
shorter lived D. koepferae, as longevity in this species
did not differ among R-CBC, P-CBC and PNC
cultures. Hormesis is a plausible explanation for the
beneficial biological effects against aging arising
from brief exposure to a lowed calorie food source
in D. buzzatii. This study shows that genetic variation
between closely related species is substantial for
dietary effects on longevity.D. koepferae, as longevity in this species
did not differ among R-CBC, P-CBC and PNC
cultures. Hormesis is a plausible explanation for the
beneficial biological effects against aging arising
from brief exposure to a lowed calorie food source
in D. buzzatii. This study shows that genetic variation
between closely related species is substantial for
dietary effects on longevity.D. buzzatii. This study shows that genetic variation
between closely related species is substantial for
dietary effects on longevity.