INVESTIGADORES
KAUFMAN Teodoro Saul
artículos
Título:
Model Studies Towards Stephaoxocanes. Construction of the 8-Oxa-1-azaphenalene Core of Stephaoxocanidine and Eletefine
Autor/es:
DARÍO A. BIANCHI; MARCOS A. CIPULLI; TEODORO S. KAUFMAN
Revista:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
Wiley
Referencias:
Lugar: Weinheim; Año: 2003 p. 4731 - 4736
ISSN:
1434-193X
Resumen:
The
construction of the polysubstituted 1H,3H-2-oxa-4-azaphenalene 4
by means of consecutive oxa-Pictet−Spengler and Jackson cyclizations is
reported. This compound contains the ABC ring system of the novel isoquinoline
alkaloids stephaoxocanidine and eletefine, found in Stephania cepharantha and
Cissampelos glaberrima. Both these species are Menispermaceæ used in
folk medicine in the Far East and Brazil.
