INVESTIGADORES
KAUFMAN Teodoro Saul
artículos
Título:
The Oxa-Pictet-Spengler Cyclization. Synthesis of Isochromanes and Related Pyran-Type Heterocycles
Autor/es:
ENRIQUE L. LARGHI; TEODORO SAUL KAUFMAN
Revista:
SYNTHESIS
Editorial:
Thieme
Referencias:
Lugar: Stuttgart; Año: 2006 p. 187 - 210
ISSN:
1414-915X
Resumen:
Compounds bearing the isochroman ring system are found in natural and synthetic products of interest. The oxa-Pictet-Spengler condensation is a valuable tool for the preparation of polysubstituted isochromans and related oxygen-bearing heterocycles. The different stagings of the oxa-Pictet-Spengler reaction, as well as the scope and limitations of this transformation, are discussed.
