INVESTIGADORES
KAUFMAN Teodoro Saul
artículos
Título:
Synthesis of the Carbon Framework of the Stephaoxocanes Employing a Sequential RCM/Pomeranz-Fritsch Approach
Autor/es:
ANDREA B. J. BRACCA; TEODORO S. KAUFMAN
Revista:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
Wiley
Referencias:
Lugar: Berlin; Año: 2007 p. 5284 - 5293
ISSN:
1434-193X
Resumen:
The syntheses of two cyclodeca[ij]isoquinoline derivatives, which embody the carbon framework of stephaoxocanidine, excentricine and the recently isolated stephalonganines A, B and C, are reported. The target tricyclic compounds were prepared from isovanillin, employing a ring-closing metathesis approach towards the synthesis of a benzocyclodecane- type common intermediate; different modifications of the Pomeranz-Fritsch protocol allowed the installation of the heterocyclic ring.
