Low iodine intake during pregnancy: relationship to placental development and head circumference in newborn.

J.L. OLIVARES; G.I. OLIVI; C. VERDASCO; V.A. ORTIZ; M. A. MAYER; J.C. CRESTO

ENDOCRINOLOGIA Y NUTRICION

ELSEVIER

Año: 2012 vol. 59 p. 326 - 330

1575-0922

Introduction: Iodine is considered to be an essential micronutrient in pregnant women. Iodine placental transport to the embryo-fetus is essential for hormone synthesis and is crucial for nervous system development. However, the relationship between iodine intake and placental weight and its potential implications for the newborn have not been studied. Material and methods:Iodine intake was analyzed in 77 pregnant women based on uri-nary iodine excretion (UIE) levels, measured using Pinoˇıs modified method (normal value,≥150g/L). Placental weight was measured (PW: normal, ≥500g). In the newborn,weight, height, and head perimeter (HP) were also measured. Placental index (PI: placental weight/newborn weight) was calculated, and was considered normal if≥0.15. Results:UIE was normal in 50 pregnant women (mean±SD, 279g/L±70.22g/L) and decrea-sed in 27 (94g/L±31.49g/L). Newborns of mothers with low UIE had a similar weight (3357g±416.30g; n: 27) to those of mothers with normal UIE (3489g±560.59g; n: 50). Forty-four percent of mothers with low UIE had PW