Cloning of an octopamine/tyramine receptor and plasticity of its expression as a function of adult sexual maturation in the male moth, Agrotis ipsilon

LINE DUPORTETS, ROMINA B. BARROZO, FRANÇOISE BOZZOLAN, CYRIL GAERTNER, SYLVIA ANTON, CHRISTOPHE GADENNE, STÉPHANE DEBERNARD

INSECT MOLECULAR BIOLOGY

WILEY-BLACKWELL PUBLISHING, INC

Año: 2010 vol. 19 p. 489 - 499

0962-1075

<!-- /* Font Definitions */ @font-face {font-family:Calibri; mso-font-alt:"Courier New"; mso-font-charset:0; mso-generic-font-family:auto; mso-font-pitch:variable; mso-font-signature:50331648 0 0 0 1 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-parent:""; margin-top:0cm; margin-right:0cm; margin-bottom:10.0pt; margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-fareast-font-family:Calibri; mso-hansi-font-family:Calibri; mso-bidi-font-family:"Times New Roman"; mso-fareast-language:EN-US;} @page Section1 {size:612.0pt 792.0pt; margin:70.85pt 70.85pt 70.85pt 70.85pt; mso-header-margin:36.0pt; mso-footer-margin:36.0pt; mso-paper-source:0;} div.Section1 {page:Section1;} --> In the male moth, Agrotis ipsilon, behavioral response and antennal lobe (AL) neuron sensitivity to the female-produced sex pheromone increase with age and juvenile hormone (JH) level. We recently showed that the neuromodulator, octopamine (OA), interacts with JH in this age-dependent olfactory plasticity. To further elucidate its role, we cloned a full cDNA encoding a protein that presents biochemical features essential to OA/tyramine receptor (AipsOAR/TAR) function. The AipsOAR/TAR transcript was detected predominantly in the antennae, the brain and more specifically in ALs where its expression level varied concomitantly with age. This expression plasticity indicates that AipsOAR/TAR might be involved in central processing of the pheromone signal during maturation of sexual behavior in A. ipsilon.