Optimizing cyanobacteria metabolic network for ethanol production

CECILIA I. PAULO; VANINA G. ESTRADA; JIMENA DI MAGGIO; MARIA SOLEDAD DIAZ

COMPUTER AIDED CHEMICAL ENGINEERING

ELSEVIER

Lugar: Amsterdam; Año: 2011 vol. 29 p. 1366 - 1371

1570-7946

This work addresses cyanobacteria Synechocystis PCC 6803 metabolic network optimization with potential gene knockouts for ethanol production as a Mixed Integer Lineal Programming problem. There is recent experimental evidence of ethanol production by fermentation of cyanobacteria, while sequestrating carbon dioxide as carbon source in photoautotrophic growth conditions. These issues make ethanol production by algae a promising alternative. The optimization of metabolic pathways gives useful insights on cellular metabolism for improving process yield by engineering cyanobacteria. optimization with potential gene knockouts for ethanol production as a Mixed Integer Lineal Programming problem. There is recent experimental evidence of ethanol production by fermentation of cyanobacteria, while sequestrating carbon dioxide as carbon source in photoautotrophic growth conditions. These issues make ethanol production by algae a promising alternative. The optimization of metabolic pathways gives useful insights on cellular metabolism for improving process yield by engineering cyanobacteria. optimization with potential gene knockouts for ethanol production as a Mixed Integer Lineal Programming problem. There is recent experimental evidence of ethanol production by fermentation of cyanobacteria, while sequestrating carbon dioxide as carbon source in photoautotrophic growth conditions. These issues make ethanol production by algae a promising alternative. The optimization of metabolic pathways gives useful insights on cellular metabolism for improving process yield by engineering cyanobacteria. Synechocystis PCC 6803 metabolic network optimization with potential gene knockouts for ethanol production as a Mixed Integer Lineal Programming problem. There is recent experimental evidence of ethanol production by fermentation of cyanobacteria, while sequestrating carbon dioxide as carbon source in photoautotrophic growth conditions. These issues make ethanol production by algae a promising alternative. The optimization of metabolic pathways gives useful insights on cellular metabolism for improving process yield by engineering cyanobacteria.