BECAS
AGUILERA PALACIOS Edna Ximena
artículos
Título:
Solvent and catalysis-free microwave transesterification of β-ketoesters and its application in the production of long-chain ester monastrol derivatives
Autor/es:
EDNA X. AGUILERA; ÁNGEL G. SATHICQ; DANIELA I. LICK; MÓNICA L. CASELLA; MARCELO C. MURGUÍA; LUIS R. PIZZIO; GUSTAVO P. ROMANELLI
Revista:
Sustainable Chemistry and Pharmacy
Editorial:
Elsevier B.V.
Referencias:
Año: 2024 vol. 37 p. 1 - 12
Resumen:
In this work we report a detailed study of the transesterification reaction of β-ketoesters in solvent-and catalyst-free conditions, using microwave irradiation. Different alcohols, including fatty alcohols, were tested to optimize the reaction conditions. Good yields, without the formation of secondary products, were observed at 150 °C. The compounds obtained were used as starting substrates in a Biginelli-type multicomponent synthesis to obtain long-chain ester monastrol derivatives, at 80 °C, with good yields, and generally free of secondary products.
