INVESTIGADORES
LORENZO PISARELLO Maria Jose
artículos
Título:
GW9662, a peroxisome proliferator-activated receptor gamma antagonist, attenuates the development of non-alcoholic fatty liver disease
Autor/es:
BAUMANN, ANJA; BURGER, KATHARINA; BRANDT, ANNETTE; STALTNER, RAPHAELA; JUNG, FINN; RAJCIC, DRAGANA; LORENZO PISARELLO, MARIA JOSE; BERGHEIM, INA
Revista:
METABOLISM-CLINICAL AND EXPERIMENTAL
Editorial:
W B SAUNDERS CO-ELSEVIER INC
Referencias:
Lugar: Philadelphia; Año: 2022
ISSN:
0026-0495
Resumen:
nsulin resistance is among the key risk factors for the development of non-alcoholic fatty liver disease (NAFLD). Recently, it has been reported that GW9662, shown to be a potent peroxisome proliferator-activated receptor gamma (PPARγ) antagonist, may improve insulin sensitivity in settings of type 2 diabetes. Here, we determined the effects of GW9662 on the development of NAFLD and molecular mechanisms involved.
