Head circumference at birth and postnatal growth trajectory in vulnerable groups from Argentina

GONZÁLEZ GARELLO, TOMÁS; BARBEITO-ANDRÉS, JIMENA; PÉREZ, ADRIANA; CUETO, GERARDO; NUÑEZ, PABLO; BONFILI, NOELIA; GONZALEZ, PAULA

American Journal of Biological Anthropology

Wiley

Año: 2024

2692-7691

Objectives: To investigate the association between the anthropometric status at birth and brain and bone growth during the first year of life. According to the brain-sparing hypothesis, we expect catch-up to be faster in head circumference (HC) than in body length.Methods: This is a longitudinal design that included Argentinian infants under12 months of age with at least three anthropometric records. We classified studyparticipants into four growth status categories according to z-scores for HC (HCZ)and length (LAZ) at birth, with z-score = 2 as a threshold. We used the Count model to describe growth trajectories in HC and length in the first year of life according to the growth status at birth. Recovery indicator for HC and length was taken as the time until the predicted growth trajectory surpassed the threshold curve predicted by z-score = 2 for age.Results: Growth models included 3399 infants. There were significant differences inthe growth parameters between groups in all cases (p < 0.05). Within the group witha low HCZ and a low LAZ at birth, HC recovery was faster than length. In the case of a low z-score for only one of the variables, newborns with a low HCZ recovered faster than individuals born with a low LAZ.Conclusions: The postnatal growth pattern in HC and length is associated with thegrowth status of HC and length at birth. As we hypothesized, the fastest postnatalrecovery occurs for HC in cases of intrauterine delayed growth.