Can the Herbicide Dicamba Produce Oxidative Stress in the Native South American fish Jenynsia lineata at Environmentally Relevant Concentrations?

VILLAGRAN, DIANA M; LOMBARDERO, LUCAS R; CRUPKIN, ANDREA C; MENDIETA, JULIETA R; MEDICI, SANDRA K; LAVARELLO, FRANCISCO; SIMONIELLO, M FERNANDA; MENONE, MIRTA L

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

SPRINGER

Lugar: Berlin; Año: 2023 vol. 111

0007-4861

Dicamba (DIC) is one of the most applied auxin herbicides worldwide. Sublethal effects in the South American nativefish Jenynsia lineata exposed to DIC concentrations close to environmental concentrations (0.03–30 µg/L) during 48 hwere analysed thorough the evaluation of catalase (CAT), glutathione S-transferase (GST), superoxide dismutase (SOD)activities and malondialdehyde (MDA) and H2O2 levels for detecting potential oxidative stress. In gills MDA increasedshowing oxidative damage probably because of an inefficient antioxidant defense. This response evidenced the importantrole of gills as an organ of direct contact with waterborne contaminants. In addition, other changes in the biomarkers ofoxidative stress were observed such as the inhibition of SOD activities in brain and the inhibition of GST in liver. Theseresults show that short- term exposures to environmentally relevant concentrations of DIC could induce sublethal effectsin native fish.