A simple method to select high superovulatory responder goats

BRUNO GALARRAGA, MARÍA MACARENA;; FERNANDEZ, JIMENA; ISABEL LACAU- MENGIDO; GONZALES BULNES A

THERIOGENOLOGY

ELSEVIER SCIENCE INC

Lugar: Amsterdam; Año: 2023 vol. 195

0093-691X

In most female mammals, a common drawback to multiple ovulation embryo transfer programs is thevariability in the superovulatory response to the multidose pFSH treatment. The aim of the present studywas to identify embryo donor goats based on their response to superovulation before the performance ofa high-cost hormonal treatment, as we have previously done in sheep. To this end, we evaluated thenumber of ovulations obtained in response to the administration of a one-shot eCG treatment andrelated it with the subsequent ovarian response to a multiple-dose pFSH treatment in 33 goats of theCriolla-Neuquina breed. Goats received a one-shot eCG treatment of 800 IU at the end of a 17-dayprogestational treatment; 9 days later, started a second 17-day progestational treatment and thenreceived a multiple-dose pFSH treatment on days 15e17 (116 mg pFSH, in six decreasing doses). Thenumber of corpora lutea (CL) per goat was recorded laparoscopically after both hormonal treatments. Onday 8 after the second pessary removal, embryos were surgically recovered and classified by quality.Results showed a significant positive correlation between the number of CL obtained in response to theeCG and pFSH treatments (r ¼ 0.41; y ¼ 0.8352x þ 6.9906; P < 0.05), although of limited value to selecthigh ovulatory responding goats, due to its low correlation value. Then, goats were grouped into high andlow ovulatory responders to the eCG (High 9; Low