UMYMFOR 05516
UNIDAD DE MICROANALISIS Y METODOS FISICOS EN QUIMICA ORGANICA
Unidad Ejecutora - UE
artículos
Título:
Synthesis and preliminary biological screening of sterol analogues as new antifungal agents against plant pathogens.
Autor/es:
ALONSO, FERNANDO; ADRIANA M CIRIGLIANO; CABRERA GABRIELA M.; RAMIREZ JAVIER
Revista:
STEROIDS
Editorial:
ELSEVIER SCIENCE INC
Referencias:
Año: 2010 vol. 75 p. 659 - 664
ISSN:
0039-128X
Resumen:
In this paper we report the synthesis of a new family of sterol analogues that have twoamidic bonds on the side chain. These azasterols were obtained by a straightforwardprocedure including an Ugi condensation that allows the facile attachment of apolyfunctionalized side chain into the steroidal framework.Some of the new compounds showed an interesting inhibitory effect on the growth oftwo pathogenic fungi involved in plant diseases.
