INVESTIGADORES
BOCCACCIO Graciela Lidia
artículos
Título:
Non-coding plasmid DNA induces IFN-gamma in vivo and suppresses autoimmune encephalomyelitis
Autor/es:
BOCCACCIO, GL; MOR, F; STEINMAN, L
Revista:
INTERNATIONAL IMMUNOLOGY
Referencias:
Año: 1999 vol. 11 p. 289 - 296
ISSN:
0953-8178
Resumen:
Regulatory sequences used in plasmids for naked DNA vaccination can modulate cytokine
production in vivo. We demonstrate here that injection of plasmid DNA can suppress the prototypic
T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis, by inducing
IFN-gamma
