INVESTIGADORES
KAUFMAN Teodoro Saul
artículos
Título:
Total Synthesis of Aqabamycin G, a Nitrophenyl Indolylmaleimide Marine Alkaloid from Vibrio sp . WMBA
Autor/es:
VARGAS, DIDIER F.; KAUFMAN, TEODORO S.; LARGHI, ENRIQUE L.
Revista:
JOURNAL OF ORGANIC CHEMISTRY
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2022
ISSN:
0022-3263
Resumen:
The first total synthesis of the marine alkaloid aqabamycin G is disclosed. The synthetic sequence involved the stepwise addition to maleimide of an indole motif and a substituted diazo-benzenoid unit derived from acetaminophen. An alternative strategy using a protected phenol is also reported.
