TAGLIAZUCCHI Mario Eugenio
Chemically Modified Nanopores and Nanochannels
MARIO TAGLIAZUCCHI; IGAL SZLEIFER
Lugar: Amsterdam; Año: 2016 p. 200
In the last years, the field of nanopores and nanochannels has grown to become a major area in modern nanotechnology. Commercially viable applications of these nanofluidic elements in sensing and filtration are now a reality and novel uses in energy conversion and catalysis are under investigation. While the first generations of solid-state nanochannels and pores were used as prepared without further chemical functionalization, researchers soon realized that chemical modification of nanopores and nanochannels has the potential to improve transport properties. Chemical functionalization allows controlling the degree of charge and hydrophobicity of the channels and it creates a handle to direct the transport of small ions, polymeric chains and large particles. Chemically modified pores and channels have the ability to respond to changes of pH, ionic strength, illumination and presence of analytes in solution. The area of chemically modified nanopores will grow further in coming years, driven by the promise of improved applications and fuelled by the availability of tools for surface modification, which chemists originally developed for planar surfaces. The present book is the first work devoted to chemically modified nanopores and it targets an audience of chemists, biomedical engineers, material and biomaterial scientists and chemical engineers, who are interested in applying the tools of chemistry to synthesize, modify, characterize, use and model nanopores. The strong chemical background of the book will make it a unique reference material in the nanopore literature, traditionally focused either on physics, biophysics and nanofabrication (solid-state nanopores) or biophysics and biology (biological ion channels and pores). Our book will cover i) the fundamentals of transport in chemically modified systems, which build on the basic knowledge required to understand transport in non-functionalized systems by incorporating concepts of soft-materials, ion transport and non-equilibrium thermodynamics, ii) an account of the different preparation and characterization techniques of chemically modified nanopores and iii) examples of application.