INVESTIGADORES
SUAREZ Sebastian
artículos
Título:
Hobartine: an indole Alkaloid from Aristotelia chilensis.
Autor/es:
CRISTIAN PAZ ROBLES; NATALIA BADILLA VIDAL; SEBASTIAN SUAREZ; RICARDO BAGGIO
Revista:
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 2014
ISSN:
0108-2701
Resumen:
The natural compound hobartine {systematic name: (1R)-3[(1S,5S)-(4,4,8-trimethylbicyclo[3.3.1]non-7-en-2-yl)methyl]2,3-dihydro-1H-indole}, C20H26N2, (I), is an indole alkaloid isolated from Aristotelia chilensis as part of a study of secondary metabolites from Chilean flora. The colourless compound has a tetracyclic structure closely related to the strongly coloured polymorphic structures discussed in Paz et al. [Acta Cryst. (2013), C69, 1509?1512] and Watson et al. [Acta Cryst. (1989), C45, 1322?1324]. The main differences reside in the absence of a keto group in (I) compared with the previous structures, as well as an endo double bond in (I) contrasting with the exo double bond found in the previous structures. The supramolecular structure of (I) in strongly related to the twofold screw axis, around which isolated chains build up, internally linked by an N?HN hydrogen bond which is the only significant intermolecular interaction present in the structure
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