INVESTIGADORES
D`ALESSIO Luciana
congresos y reuniones científicas
Título:
Prevalence of Psychotic Disorders in Epilepsy Surgery Candidates with Refractory Temporal Lobe Epilepsy
Autor/es:
D`ALESSIO LUCIANA, GIAGANTE BRENDA, PAPAYANNIS CRISTINA, ODDO SILVIA, CONSALVO DAMIÁN, KAUFFMAN MARCELO, SILVA WALTER, DONNOLI VICENTE, ZIEHER LUIS MARÍA, LÓPEZ – COSTA JUAN JOSÉ, KOCHEN SILVIA.
Lugar:
Montevideo
Reunión:
Congreso; Congreso Latinoamericano de Epilepsia; 2008
Institución organizadora:
Liga Internacional Contra la Epilepsia
Resumen:
Introduction: Epilepsy Surgery Candidates and in particular, Refractory Temporal Lobe Epilepsy (RTLE) patients, have a high risk to develop psychotic disorders. At the moment, not many studies using current psychiatric nosography (DSM IV or ICD 10) have been done. Objectives: To determine the prevalence for psychotic disorders in surgical candidates of epilepsy surgery and analyze the risk factors for psychosis in RTLE patients. Methods: Between 2001 – 2007, 403 surgical candidates to epilepsy were admitted. Psychiatric evaluations consisted in structural interviews of DSM IV (SCID I y II) before surgery. 123 patients with RTLE were selected according inclusion and exclusion criteria. 63 patients met criteria for psychotic disorders (PG) and 60 RTLE patients (CG) had no criteria for any type of psychotic disorders, and were considered a control group. Clinical variables of epileptic syndrome were compared between the groups. Logistic regression was performed. Results: Criteria for psychotic disorders in axis I were found in 16% of the surgical candidates admitted. More frequent psychotic subtype were transient forms of interictal and postictal psychotic disorders (less than 6 months). Bilateral hippocampal sclerosis, status epilepticus and a longer duration of epilepsy were risk factors for psychoses. Conclusions: Psychosis is a frequent disorder in epilepsy surgery candidates. Brief and transient types of psychosis are the most common types. More severe epilepsy with longer evolution may increase the vulnerability to develop psychoses in patients with refractory temporal epilepsy. Key words: Psychotic disorders. Temporal lobe epilepsy. Refractory epilepsy. Epilepsy surgery.