Mejoramiento del pelaje de ratas Sprague-Dawley alimentadas con Spirulina platensis (Cyanobacteria)

ANA MARIA STELLA; MONICA STORNI DE CANO; STEYERTHAL; M. J. PIANTANIDA; ANDRES ALBERTO RODRIGUEZ; GLORIA ZULPA DE CAIRE

Buenos Aires, Argentina

Jornada; Reunión Anual de Investigación dedicada a la Dermatología 1999; 1999

Spirulina platensis is a Cyanobacteria with a high content of protein, vitamins and fatty acids, which justify its use as dietary supplement. The aim of this work was to evaluate the effect of Spirulina platensis ingestion on growth, morphology and metabolism of Sprague-Dawley rats. Twelve female rats, 21 days old received, 2.o ml of water without (Control, n 6) and with 300 mg dry-powerdered Spirulina plantesis (Treated, n = 6), by gastric probe as well as rodent commercial food and water ad libitum, during 50 days. The following parameters were evaluated. Commercial food ingestion per day, body weight, width of the head, length of the tail. Hipophysis, liver, right and left kidney, caecum, right and left ovary, uterus, pancreas,spleen and stomach were also weighed. Width and length of hair from external hear region were measured. Blood was obtained by cardiac punction HDL, LDL and total cholesterol, aspartate amino transpherase-GOT (AST) -, chlolinesterase (ChE) and glutamyl transpherase (g-GT), phosphatase alkaline, uremia were measured in the serum; as well as liver 5-aminolevulinate dehidratase (ALA-D) and porphyrin content in liver and hair. Rats feeding with Spirulina platensis did not produced significant differences in growth during treatment. Body weight, hair size and teail length did not show differences either. Length (10.00±1.20mm) and width (80.00±10.00mm) of the treated hair were significantly higher (p<0.05) than control (length= 5.000±0.850mm, wide = 50.00±10.00 mm). Hair was bright and length/width relation was 1.15 times higher in treated rats. Use of Spirulina platensis in Sprague-Dawley rats feedings did not probably due to the stimulation of lactic flora so favouring a better absorption of nutrients. Vitamins and amino acids contributed by this dietary supplement would also favour the growth of hair as well as the development of the cuticle.