PROIMI   05436
PLANTA PILOTO DE PROCESOS INDUSTRIALES MICROBIOLOGICOS
Unidad Ejecutora - UE
capítulos de libros
Título:
Novel Sources of Antimicrobials from Pristine and Poorly Explored Environments. The Patagonia Microbiota Case
Autor/es:
ARNAU V.G.; ACOSTA, F.; SANCHEZ L. A; DANILOVICH, M.E; DELGADO O.D.
Libro:
Biology and Biotechnology of Patagonian Microorganisms
Editorial:
Springer International Publishing AG
Referencias:
Lugar: Berlin; Año: 2016; p. 1 - 351
Resumen:
Antimicrobial compounds are molecules widespread in life forms to mediatecompetition, and their industrial production could be important for thepotential use as preservatives in food, cosmetical and pharmaceuticalindustries. Pathogen resistance causes high mortality rates in hospitals andimportant economics losses in health institutions. Pathogens such asmethicillin-resistant Staphylococcusaureus, penicillin-resistant Streptococcuspneumoniae and beta-lactam resistant Pseudomonasaeruginosa are the most common examples. This worldwide problem requiresthe discovery of new molecules with antibiotic activity, effective therapeuticsstrategies, and research of promising targets. Most antibiotics came up fromscreening programs of natural sources, including the isolation of newmicroorganisms. Extremophile microorganisms are valuable source for novelsbiomolecules with unusual properties, including antimicrobial activity. Due tothe harsh conditions, Patagonian, sub-Antarctic and Antarctic environments areideal places for bioprospecting. Patagonia is a sparsely populated regionlocated at the southern end of South America, shared by Argentina and Chile. Overall climate is cool anddry; the east coast is warmer than the west, especially in summer, due to abranch of the southern equatorial current that reaches its shores, whereas thewest coast is washed by a cold current. Cold environments could be a suitablesource of microorganisms with ability to produce cold-active antimicrobialscompounds with potential use in biotechnology.