INVESTIGADORES
GALLO Loreana Carolina
artículos
Título:
A comparative study of spray-dried medicinal plant aqueous extracts. Drying performance and product quality
Autor/es:
GALLO LOREANA; MARÍA VERÓNICA RAMIREZ RIGO; JULIANA PIÑA; VERÓNICA BUCALÁ
Revista:
CHEMICAL ENGINEERING RESEARCH & DESIGN
Editorial:
INST CHEMICAL ENGINEERS
Referencias:
Año: 2015 vol. - p. 1 - 36
ISSN:
0263-8762
Resumen:
In the manufacture of herbalmedicinal tablets, dried plant extracts are employed as the therapeuticingredient. These powders, usually obtained by spray drying, are typically hygroscopicand possess poor flow and compactability for the manufacture of tablets bydirect compression (DC). Besides, spray-drying operating conditions and liquidfeed composition are reported to be dependent on the herbal medicine.Consequently, the production of dried implies long new product developmenttimes. Therefore, the goal of this paper was to: (a) provide recommendations asinitial production point of herbal powders suitable for DC by spray drying and(b) study the powder properties to identify those that are affected spraydrying by the extract nature. Particularly, a unique set of operatingconditions was found to be appropriate to produce powders of seven differentmedicinal plant extracts. In fact, all the Tablets spray-dried products showedadequate flowability, stability and compactability.Powders properties, as particlesize and morphology, moisture content, hygroscopicity, flowability and compacthardness were not a function of the type of herb. Conversely, the process yieldand glass transition temperature, particle and bulk densities, powder composition,compact porosity, wetting and disintegration times were found to be dependenton the chemical nature of the herbs.