INVESTIGADORES
DIAZ Maria Soledad
congresos y reuniones científicas
Título:
Large-scale Metabolic Network Design Under Stability Constraints for Sustainable Biofuel Production
Autor/es:
JIMENA DI MAGGIO; A. BLANCO; A. BANDONI; MARIA SOLEDAD DIAZ
Lugar:
Buenos Aires
Reunión:
Congreso; ALIO/INFORMS 2010 Joint International Meeting; 2010
Resumen:
We propose an eigenvalue optimization approach to ensure steady state stability of the EMP pathway, the PP pathway, phosphotranferase system and fermentation pathways of Escherichia coli to maximize ethanol production. The model consists of 26 differential equations that represent dynamic mass balances of extracellular glucose, intracellular metabolites and fermentation products, 37 kinetic rate expressions and additional correlations for co-metabolites temporal profiles.