INVESTIGADORES
DIAZ Maria Soledad
artículos
Título:
Design and optimization of poly(hydroxyalkanoate)s production plants using alternative substrates
Autor/es:
RAMOS, FERNANDO D.; DELPINO, CLAUDIO A.; VILLAR, MARCELO A.; DIAZ, M. SOLEDAD
Revista:
BIORESOURCE TECHNOLOGY
Editorial:
ELSEVIER SCI LTD
Referencias:
Año: 2019 vol. 289
ISSN:
0960-8524
Resumen:
In this work, we propose a Mixed Integer Nonlinear Programming (MINLP) model to determine the optimal design of a poly(hydroxyalkanoate)s (PHAs) production plant configuration. The superstructure based optimization model considers different carbon sources as raw material: glycerol (crude and purified), corn starch, cassava starch, sugarcane sucrose and sugarcane molasses. The PHA extraction section includes four alternatives: the use of enzyme, solvent, surfactant-NaOCl or surfactant-chelate. Model constraints include detailed capital cost for equipment, mass and energy balances, product specifications and operating bounds on process units. The resulting MINLP model maximizes the project net present value (NPV) as objective function and it is implemented in an equation oriented environment. Optimization results show the sugarcane-enzyme option as the most promising alternative (NPV = 75.01 million USD) for PHAs production with an energy consumption of 22.56 MJ/kg PHA and a production cost of 3.02 USD/kg PHA. Furthermore, an economic sensitivity analysis is performed.