Composition and Antinflammatory Activity from Atriplex undulata (Moq) D. Dietr. (Chenopodiaceae)

RODRIGUEZ, SILVANA; VIÑA M. D; ANA PAULA MURRAY; LEIRO J.M.

Fortaleza

Congreso; XX° Italo-Latinamerican Congress of Ethnomedicine; 2011

Sociedad Italolatinoamericana de Etnomedicina

Atriplex undulata commonly known as Zampa crespa or Cachiyuyo, is an endemic species that is found in Patagonia and the south of Buenos Aires province and which is tradicionally used as an astringent and antiequimotic. As a part of our continuing search for biologically active compounds, we have attempted to isolate and characterize the active principle responsible for antinflammatory activity from the ethanolic extract from the aerial parts of A. undulata, growing wild in Bahía Blanca, Argentina. Based upon the results, it was found that the ethyl acetate partition showed the greatest antinflammatory activity with a lower IC50 value than the other partitions. This antinflammatory effect could be explained, at least in part, by the presence in this fraction of quercetin and kaempferol, which showed significantly inhibition of nitrite production5. These results allow continuing with the chemical study and pharmacology of this plant