INVESTIGADORES
DIAZ Luis Adrian
artículos
Título:
Seroprevalence of St. Louis Encephalitis Virus and West Nile Virus (Flavivirus, Flaviviridae) in Horses, Uruguay
Autor/es:
ANALÍA BURGUEÑO; LORENA SPINSANTI; LUIS ADRIÁN DÍAZ; MARÍA ELISA RIVAROLA; JUAN ARBIZA; MARTA CONTIGIANI; ADRIANA DELFRARO
Revista:
BioMed Research International
Editorial:
Hindawi Publishing Corporation
Referencias:
Lugar: New York; Año: 2013 vol. 2013 p. 1 - 5
ISSN:
2314-6141
Resumen:
St. Louis encephalitis virus (SLEV) and West Nile virus (WNV) belong to the Japanese encephalitis antigenic complex (Flavivirus genus, Flaviviridae family). They show antigenic close relationships and share many similarities in their ecology. Both are responsible for serious human diseases. The aim of this study was to investigate the presence of neutralizing antibodies to these viruses in horses from Uruguay. To do this, 425 horse sera were collected in 2007 and analyzed by plaque reduction neutralization tests. As a result, 205 sera (48.2%) were found positive for SLEV, with titers ranging between 10 and 80. Two sera remained inconclusive, since they showed low titers to WNV and SLEV (10 and 20), not allowing us to demonstrate activity of WNV in our territory. This is the first report of circulation of SLEV in horses in Uruguay.