Real-World Variability in the Prediction of Intracranial Aneurysm Wall Shear Stress: The 2015 International Aneurysm CFD Challenge

VALEN-SENDSTAD, KRISTIAN; BERGERSEN, ASLAK W.; SHIMOGONYA, YUJI; GOUBERGRITS, LEONID; BRUENING, JAN; PALLARES, JORDI; CITO, SALVATORE; PISKIN, SENOL; PEKKAN, KEREM; GEERS, ARJAN J.; LARRABIDE, IGNACIO; RAPAKA, SAIKIRAN; MIHALEF, VIOREL; FU, WENYU; QIAO, AIKE; JAIN, KARTIK; ROLLER, SABINE; MARDAL, KENT-ANDRE; KAMAKOTI, RAMJI; SPIRKA, THOMAS; ASHTON, NEIL; REVELL, ALISTAIR; ARISTOKLEOUS, NICOLAS; HOUSTON, J. GRAEME; TSUJI, MASANORI; ISHIDA, FUJIMARO; MENON, PRAHLAD G.; BROWNE, LEONARD D.; BRODERICK, STEPHEN; SHOJIMA, MASAAKI; KOIZUMI, SATOSHI; BARBOUR, MICHAEL; ALISEDA, ALBERTO; MORALES, HERNÁN G.; LEFÈVRE, THIERRY; HODIS, SIMONA; AL-SMADI, YAHIA M.; TRAN, JUSTIN S.; MARSDEN, ALISON L.; VAIPPUMMADHOM, SREEJA; EINSTEIN, G. ALBERT; BROWN, ALISTAIR G.; DEBUS, KRISTIAN; NIIZUMA, KUNIYASU; RASHAD, SHERIF; SUGIYAMA, SHIN-ICHIRO; OWAIS KHAN, M.; UPDEGROVE, ADAM R.; SHADDEN, SHAWN C.; CORNELISSEN, BART M. W.; MAJOIE, CHARLES B. L. M.; BERG, PHILIPP; SAALFIELD, SYLVIA; KONO, KENICHI; STEINMAN, DAVID A.

Cardiovascular Engineering and Technology

Springer

Año: 2018 vol. - p. 1 - 1

1869-408X

PURPOSE:Image-based computational fluid dynamics (CFD) is widely used to predict intracranial aneurysm wall shear stress (WSS), particularly with the goal of improving rupture risk assessment. Nevertheless, concern has been expressed over the variability of predicted WSS and inconsistent associations with rupture. Previous challenges, and studies from individual groups, have focused on individual aspects of the image-based CFD pipeline. The aim of this Challenge was to quantify the total variability of the whole pipeline.METHODS:3D rotational angiography image volumes of five middle cerebral artery aneurysms were provided to participants, who were free to choose their segmentation methods, boundary conditions, and CFD solver and settings. Participants were asked to fill out a questionnaire about their solution strategies and experience with aneurysm CFD, and provide surface distributions of WSS magnitude, from which we objectively derived a variety of hemodynamic parameters.RESULTS:A total of 28 datasets were submitted, from 26 teams with varying levels of self-assessed experience. Wide variability of segmentations, CFD model extents, and inflow rates resulted in interquartile ranges of sac average WSS up to 56%, which reduced to