KOCHEN Sara Silvia
congresos y reuniones científicas
Memory Analysis in Temporal Lobe Epilepsy Patients, With and Without Hippocampal Sclerosis
ODDO, S, SOLIS, P, LOMLOMDJIAN, C, GIAGANTE, B, CONSALVO, D, SILVA, W, PAPAYANNIS, C, CENTURION, E, SALGADO, P, D'ALESSIO, L, SAIDON, P, KOCHEN, S
Congreso; 26th International Epilepsy Congress; 2005
Purpose: Mesial temporal lobe epilepsy and hippocampal sclerosis syndrome (MTLE+HE) presents material-specific episodic memory deficits, due to hippocampal system damage produced by the lesion. This damage is associated with different variables like epilepsy years of evolution, age of onset and seizure frequency. The aim of this study is to analyse hippocampal sclerosis involvement as the probable cause of memory deficit, comparing results of neuropsychological evaluation in MTLE+HE patients and temporal lobe epilepsy patients with a lesion non HE. Methods: We selected 123 patients with temporal lobe epilepsy, divided into 2 groups: 101 patients with MTLE+HE and 22 patients with temporal lesion non HE. We used the following neuropsychological protocol: WAIS-R (IQ), Edinburgh questionnaire, Rey Auditory Verbal Learning Test, List Learning Test, Rey complex figure. Boston Naming Test, Wisconsin Card Sorting Test, Trail Making Test (A y B) and verbal fluency. Statistical analysis: an ANOVA test was used to analyse data and with significance variables we applied a chi square test. Results: The MTLE+HE group presented a significantly more epilepsy years of evolution (p=0.04), a lower age of onset (p=0.01) and more memory deficit (p=0.004), than the temporal lesion non HS group of patients. Conclusion: Our findings indicate that memory deficits on MTLE+HE patients would be directly related with HE as was reported by other authors.