KOCHEN Sara Silvia
ApoE ε4 is not associated with postictal confusion in patients with mesial temporal lobe epilepsy with hippocampal sclerosis
KAUFFMAN M., PEREIRA DE SILVA N., CONSALVO D., KOCHEN S
ELSEVIER SCIENCE BV
Año: 2009 vol. 85 p. 311 - 311
Abstract A previous report found an association between ApoE isoforms and postictal confusion in medically intractable temporal lobe epilepsy (TLE). We performed a molecular epidemiology study in an independent sample of 77 TLE patients. We failed to replicate the original allelic association between ApoE ε4 allele and postictal confusion in our population (χ2 = 1.67; d.f. =1; p=0.2). Thus, the association between ApoE ε4 allele and postictal confusion still needs to be fully investigated in different and independent populations.