INVESTIGADORES
GONZALEZ Maria Micaela
congresos y reuniones científicas
Título:
New Insights into the Photophysics and Photochemistry of Harmalol in Aqueous Media
Autor/es:
JUAN GABRIEL YAÑUK; MARIA PAULA DENOFRIO; MARIA LIS ALOMAR; MARIA MICAELA GONZALEZ; ROSA ERRA-BALSELLS; FRANCO M. CABRERIZO.
Lugar:
Córdoba
Reunión:
Congreso; 16th international Congress on Photobiology; 2014
Resumen:
Harmalol is a naturally occurring alkaloid that belongs to the family of b-carbolines (bCs). bCs comprise both fully aromatic alkaloids and partially reduced derivatives such as 3,4-dihydro and 1,2,3,4-tetrahydro-bCs. In terms of its chemical structure, harmalol is a 3,4-dihydro-bC. During the last decades, the photophysics and photochemistry of some bCs, in aqueous media,has been well investigated. Briefly, in aqueous solution, these alkaloids may show several acid-base equilibria. However, for some dihydro- and tetrahydro-bCs, the information published in the literature is, in somehow, contradictory, negligible or null. In the present work we have investigated the acid-base equilibria and species present in the pH range of 2-13. The corresponding pKa values, chemical structure of each harmalol acid-base specie, as well as the corresponding absorption and emission spectra observed in aqueous solution are reported. Moreover, the pH-effect on the thermal and photochemical stability of harmalol is also reported.