INQUINOA 21218
INSTITUTO DE QUIMICA DEL NOROESTE
Unidad Ejecutora - UE
artículos
Título:
ANTIMICROBIAL ACTIVITIES OF SESQUITERPENE LACTONES AND INOSITOL DERIVATIVES FROM HYMENOXYS ROBUSTA
Autor/es:
ANTONIO M. FORTUNA, ZAIDA N. JUÁREZ, HORACIO BACH, ANOUF NEMATALLAH, YOSSEF AV-GAY, EUGENIO SÁNCHEZ-ARREOLA, E.C.M. DE RISCALA, CÉSAR A.N. CATALÁN, S. TURBAY, LUIS R. HERNÁNDEZ
Revista:
PHYTOCHEMISTRY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2011 vol. 72 p. 2413 - 2418
ISSN:
0031-9422
Resumen:
Six compounds from the aerial parts of the Argentinean plant Hymenoxys robusta (Rusby) K. Parker were isolated and their structures elucidated using extensive spectroscopic analyses. These compounds comprise two new inositol derivatives, four 3,4-seco-pseudoguaianolides, one of them known as vermeerin, and the rest identified as new natural compounds. Bioactivity assays of these compounds against bacterial and fungal pathogens showed that only vermeerin possessed antimicrobial activity specific against Staphylococcus aureus, and showed no toxicity when exposed to human-derived macrophages.
