PERSONAL DE APOYO
FANELLI Silvia Laura
congresos y reuniones científicas
Título:
Alcohol induction of liver nuclear ethanol and N-Nitrosodimethylamine (NDMA) metabolism to reactive metabolites
Autor/es:
MI DÍAZ GÓMEZ, E. VALLES, SL FANELLI, AMA DELGADO DE LAYÑO, GD CASTRO AND JA CASTRO.
Lugar:
Estambul, Turquía
Reunión:
Congreso; EUROTOX 2001; 2001
Institución organizadora:
European Societies of Toxicology
Resumen:
In previous studies from our laboratory we reported the presence in highly purified liver nuclei, free of contamination with other organelles, of an ethanol metabolizing system able to lead to acetaldehyde and 1- hydroxyethyl free radicals. In the present study we tested wether this NEMS is inductible by chronic alcohol administration on rats and wether these nucle also have increased ability of bioactivate NDMA.
