INVESTIGADORES
SOIZA REILLY Mariano
artículos
Título:
Transcriptional preservation of serotonergic connectivity may shed light on neurodegeneration
Autor/es:
SOIZA-REILLY, M
Revista:
TRENDS IN NEUROSCIENCES
Editorial:
ELSEVIER SCIENCE LONDON
Referencias:
Lugar: Londres; Año: 2022 vol. 45 p. 563 - 565
ISSN:
0166-2236
Resumen:
In a recent study, Kitt, Tabuchi, and colleagues unveiled a novel function of an early-stage transcriptional network to maintain the adult integrity of serotonergic connectivity. Reported axonal and synaptic morphological alterations in serotonin (5-HT) neurons after selective inactivation of Lmx1b/Pet1 transcriptional networks may help to understand aging and neurodegenerative processes.
