FETTWEIS, GREGORY; JOHNSON, THOMAS A.; ALMEIDA-PRIETO, BRIAN; WELLER-PÉREZ, JULIÁN; PRESMAN, DIEGO M.; HAGER, GORDON L.; ALVAREZ DE LA ROSA, DIEGO

The mineralocorticoid receptor forms higher order oligomers upon DNA binding

PROTEIN SCIENCE; Año: 2024 vol. 33

STORTZ, MARTIN; PRESMAN, DIEGO M.; LEVI, VALERIA

Transcriptional condensates: a blessing or a curse for gene regulation?

Communications Biology; Año: 2024 vol. 7

PRESMAN, DIEGO M.; BELÉN BENITEZ; LAFUENTE, AGUSTINA L.; VÁZQUEZ LAREU, ALEJO

Chromatin structure and dynamics: one nucleosome at a time

HISTOCHEMISTRY AND CELL BIOLOGY.; Año: 2024

WAGH, KAUSTUBH; STAVREVA, DIANA A.; JENSEN, RIKKE A. M.; PAAKINAHO, VILLE; FETTWEIS, GREGORY; SCHILTZ, R. LOUIS; WÜSTNER, DANIEL; MANDRUP, SUSANNE; PRESMAN, DIEGO M.*; UPADHYAYA, ARPITA*; HAGER, GORDON L.*

Dynamic switching of transcriptional regulators between two distinct low-mobility chromatin states

Science Advances; Año: 2023 vol. 9

STORTZ, MARTIN; OSES, CAMILA; VÁZQUEZ ECHEGARAY, CAMILA; PECCI, ADALI; GUBERMAN, ALEJANDRA; PRESMAN, DIEGO M.*; LEVI, VALERIA*

SOX2 modulates the nuclear organization and transcriptional activity of the glucocorticoid receptor.

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2022 vol. 434

ALBA JIMENEZ-PANIZO; ANDREA ALEGRE-MARTÍ; THEOPHILUS TETTEY; GREGORY FETTWEIS; MONTSERRAT ABELLA; ROSA ANTÓN; THOMAS A JOHNSON; KIM, SOHYOUNG; R. LOUIS SCHILTZ; ISRAEL NUÑEZ-BARRIOS; JOAN FONT-DÍAZ; CARME CAELLES; ANNABEL F. VALLEDOR; PALOMA PÉREZ; ANA M. ROJAS; JUAN FERNÁNDEZ-RECIO; DIEGO M PRESMAN; GORDON L. HAGER; PABLO FUENTES-PRIOR; EVA ESTÉBANEZ-PERPIÑÁ

The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities

NUCLEIC ACIDS RESEARCH; Lugar: Oxford; Año: 2022

JOHNSON, THOMAS A.; PAAKINAHO, VILLE; KIM, SOHYOUNG; HAGER, GORDON L.; PRESMAN, DIEGO M.

Genome-wide binding potential and regulatory activity of the glucocorticoid receptor’s monomeric and dimeric forms

NATURE COMMUNICATIONS; Año: 2021 vol. 12

STORTZ, MARTIN*; PRESMAN, DIEGO M.*; PECCI, ADALI*; LEVI, VALERIA*

Phasing the intranuclear organization of steroid hormone receptors

BIOCHEMICAL JOURNAL; Año: 2021 vol. 478 p. 443 - 461

GARCIA, DAVID A.; JOHNSON, THOMAS A.; PRESMAN, DIEGO M.; FETTWEIS, GREGORY; WAGH, KAUSTUBH; RINALDI, LORENZO; STAVREVA, DIANA A.; PAAKINAHO, VILLE; JENSEN, RIKKE A.M.; MANDRUP, SUSANNE; UPADHYAYA, ARPITA; HAGER, GORDON L.

An intrinsically disordered region-mediated confinement state contributes to the dynamics and function of transcription factors

MOLECULAR CELL; Año: 2021 p. 1 - 15

DAVID A. GARCIA; GREGORY FETTWEIS; DIEGO M PRESMAN*; VILLE PAAKINAHO; CHRISTOPHER JARZYNSKI; ARPITA UPADHYAYA; GORDON L. HAGER

Power-law behaviour of transcription factor dynamics at the single-molecule level implies a continuum affinity model

NUCLEIC ACIDS RESEARCH; Año: 2021 vol. 49 p. 6605 - 6620

STORTZ, MARTIN; PECCI ADALI; PRESMAN, DIEGO M.*; LEVI, VALERIA*

Unraveling the Molecular Interactions Involved in the Formation of Glucocorticoid Receptor Foci

BMC BIOLOGY; Lugar: Londres; Año: 2020

DIEGO M PRESMAN

¿El OCASO DEL MODELO DISOCIADO DE ACCION GLUCOCORTICOIDEA?

Anales de la Academia Nacional de Ciencias Exactas, Físicas y Naturales de Buenos Aires; Año: 2020 p. 88 - 101

ERIK W. MARTIN; SAYANTAN CHAKRABORTY; DIEGO M. PRESMAN; FRANCESCO TOMASSONI ARDORI; KYU- SEON OH; MARY KAILEH; LINO TESSAROLLO; MYONG-HEE SUNG

Assaying Homodimers of NFkB in Live Single Cells

Frontiers in Immunology; Lugar: Lausanne; Año: 2019 vol. 10

MARIA FLORENCIA OGARA; RODRÍGUEZ-SEGUÍ, SANTIAGO A.; MARINI, MELISA; A. SILVINA NACHT; MARTÍN STORTZ; VALERIA LEVI; DIEGO M PRESMAN; GUILLERMO VICENT; ADALI PECCI

The Glucocorticoid Receptor Interferes with Progesterone Receptor-Dependent Genomic Regulation in Breast Cancer Cells

NUCLEIC ACIDS RESEARCH; Lugar: Oxford; Año: 2019

PAAKINAHO, VILLE; JOHNSON, THOMAS A.; PRESMAN, DIEGO M.*; HAGER, GORDON L.*

Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome

GENOME RESEARCH; Año: 2019 vol. 29 p. 1223 - 1234

PAAKINAHO, VILLE; SWINSTEAD, ERIN E.; PRESMAN, DIEGO M.; GRØNTVED, LARS; HAGER, GORDON L.

Meta-analysis of Chromatin Programming by Steroid Receptors

Cell Reports; Año: 2019 vol. 28 p. 3523 - 3534

TAVES, MATTHEW D.; MITTELSTADT, PAUL R.; PRESMAN, DIEGO M.; HAGER, GORDON L.; ASHWELL, JONATHAN D.

Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus

Cell Reports; Año: 2019 vol. 26 p. 3629 - 6342

STAVREVA, DIANA A.; GARCIA, DAVID A.; FETTWEIS, GREGORY; GUDLA, PRABHAKAR R.; ZAKI, GEORGE F.; SONI, VIKAS; MCGOWAN, ANDREW; WILLIAMS, GENEVA; HUYNH, ANH; PALANGAT, MURALI; SCHILTZ, R. LOUIS; JOHNSON, THOMAS A.; PRESMAN, DIEGO M.; FERGUSON, MATTHEW L.; PEGORARO, GIANLUCA; UPADHYAYA, ARPITA; HAGER, GORDON L.

Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility

MOLECULAR CELL; Lugar: United States; Año: 2019

PECCI, ADALI; ALVAREZ, LAUTARO D.; PRESMAN, DIEGO M.; BURTON, GERARDO

21-hydroxy-6,19-epoxyprogesterone: a Promising Therapeutic Agent and a Molecular Tool for Deciphering Glucocorticoid Action

MINI-REVIEWS IN MEDICINAL CHEMISTRY; Año: 2018 vol. 18 p. 428 - 438

STORTZ, MARTIN; PRESMAN, DIEGO M.; BRUNO, LUCIANA; ANNIBALE, PAOLO; DANSEY, MARIA V.; BURTON, GERARDO; GRATTON, ENRICO; PECCI, ADALI; LEVI, VALERIA

Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape

Scientific Reports; Año: 2017 vol. 7

DIEGO M PRESMAN*; GORDON L. HAGER

More than meets the dimer: What is the quaternary structure of the glucocorticoid receptor?

Transcription; Año: 2017 vol. 8 p. 32 - 39

PAAKINAHO, VILLE*; PRESMAN, DIEGO M.*; BALL, DAVID A.; THOMAS A. JOHNSON; R. LOUIS SCHILTZ; PETER LEVITT; DAVIDE MAZZA; TATSUYA MORISAKI; KARPOVA, TATIANA S.; HAGER, GORDON L.

Single-molecule Analysis of Glucocorticoid Receptor and Cofactor Action in Living Cells

NATURE COMMUNICATIONS; Año: 2017

PRESMAN, DIEGO M.; BALL, DAVID A.; PAAKINAHO, VILLE; GRIMM, JONATHAN B.; LAVIS, LUKE D.; KARPOVA, TATIANA S.; HAGER, GORDON L.

Quantifying transcription factor binding dynamics at the single-molecule level in live cells

METHODS; Año: 2017

ÁLVAREZ, LAUTARO DAMIÁN; PRESMAN, DIEGO MARTÍN; PECCI, ADALÍ

Molecular dynamics simulations of the glucocorticoid receptor DNA-binding domain suggest a role of the lever-arm mobility in transcriptional output

PLOS ONE; Año: 2017 vol. 12

GOLDSTEIN, IDO; BAEK, SONGJOON; PRESMAN, DIEGO M.; PAAKINAHO, VILLE; SWINSTEAD, ERIN E.; HAGER, GORDON L.

Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response

GENOME RESEARCH; Año: 2017 vol. 27 p. 427 - 439

ERIN E. SWINSTEAD; TINA B. MIRANDA; VILLE PAAKINAHO; SONGJOON BAEK; IDO GOLDSTEIN; MARY HAWKINS; TATIANA S. KARPOVA; DAVID BALL; DAVIDE MAZZA; LUKE DAVIS; JONATHAN GRIMM; TATSUYA MORISAKI; LARS GRØNTVED; DIEGO M PRESMAN; GORDON L. HAGER

Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions

CELL; Lugar: United States; Año: 2016 vol. 165 p. 593 - 605

DIEGO M PRESMAN*; SOURAV GANGULY; R. LOUIS SCHILTZ; THOMAS A. JOHNSON; TATIANA S. KARPOVA; GORDON L. HAGER*

DNA-binding Triggers Tetramerization of the Glucocorticoid Receptor in Live Cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2016 vol. 113 p. 8236 - 8241

ERIN E. SWINSTEAD; VILLE PAAKINAHO; DIEGO M PRESMAN; GORDON L. HAGER

Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective

BIOESSAYS; Lugar: New York; Año: 2016

DIEGO Y. GRINMAN; LEONARDO ROMORINI; DIEGO M. PRESMAN; LUCIANA ROCHA-VIEGAS; OMAR A. COSO; CARLOS DAVIO; ADALI PECCI

Role of 3'-5'-cyclic adenosine monophosphate on the epidermal growth factor dependent survival in mammary epithelial cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2015

SERENA MURATCIOGLU; DIEGO M. PRESMAN*; JOHN R. POOLEY*; LARS GRØNTVED; GORDON L. HAGER; RUTH NUSSINOV; OZLEM KESKIN; ATTILA GURSOY

Structural modeling of GR interactions with SWI/SNF chromatin remodeling complex and C/EBP

BIOPHYSICAL JOURNAL; Lugar: United States; Año: 2015 vol. 109 p. 1227 - 1239

DIEGO M. PRESMAN; M. FLORENCIA OGARA; MARTÍN STORTZ; LAUTARO D. ALVAREZ; JOHN R. POOLEY; R. LOUIS SCHILTZ; LARS GRØNTVED; THOMAS A. JOHNSON; PAUL R. MITTELSTADT; JONATHAN D. ASHWELL; SUNDAR GANESAN; GERARDO BURTON; VALERIA LEVI; GORDON L. HAGER; ADALI PECCI

Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor.

PLOS BIOLOGY; Lugar: San Francisco; Año: 2014 vol. 12

DIEGO M PRESMAN; VALERIA LEVI; OMAR PIGNATARO; ADALI PECCI

Melatonin inhibits glucocorticoid-dependent GR-TIF2 interaction in newborn hamster kidney (BHK) cells.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2012 vol. 349 p. 214 - 221

DIEGO M. PRESMAN; LAUTARO D. ALVAREZ; VALERIA LEVI; SILVINA EDUARDO; MICHELLE A. DIGMAN; MARCELO A. MARTÍ; ADRIANA S. VELEIRO; GERARDO BURTON; ADALI PECCI

Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids

PLOS ONE; Lugar: San Francisco, CA 94111; United States; Año: 2010 vol. 5

ALVAREZ LAUTARO D; MARTÍ MARCELO A; VELEIRO ADRIANA S; PRESMAN DIEGO M; ESTRIN DARÍO A; PECCI ADALI; BURTON GERARDO

Exploring the Molecular Basis of Action of the Passive Antiglucocorticoid 21-Hydroxy-6,19-epoxyprogesterone

JOURNAL OF MEDICINAL CHEMISTRY; Año: 2008 vol. 13 p. 1352 - 1360

PRESMAN DIEGO M; HOIJMAN ESTEBAN; CEBALLOS NORA R; GALIGNIANA MARIO D; PECCI ADALI

Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes

ENDOCRINOLOGY; Año: 2006 vol. 147 p. 5452 - 5459