INVESTIGADORES
CUCHER Marcela Alejandra
artículos
Título:
Cystic echinococcosis in South America: systematic review of species and genotypes of Echinococcus granulosus sensu lato in humans and natural domestic hosts
Autor/es:
CUCHER M; MACCHIAROLI N; BALDI G; CAMICIA F; PRADA L; MALDONADO L; AVILA HG; FOX A; GUTIERREZ A; NEGRO P; LOPEZ R; JENSEN O; ROSENZVIT M; KAMENETZKY L
Revista:
TROPICAL MEDICINE AND INTERNATIONAL HEALTH
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 2016 vol. 21 p. 166 - 175
ISSN:
1360-2276
Resumen:
objective To systematically review publications on Echinococcus granulosus sensu lato species/genotypes reported in domestic intermediate and definitive hosts in South America and in humancases worldwide, taking into account those articles where DNA sequencing was performed; and toanalyse the density of each type of livestock that can act as intermediate host, and features of medicalimportance such as cyst organ location.methods Literature search in numerous databases. We included only articles where samples weregenotyped by sequencing since to date it is the most accurate method to unambiguously identify allE. granulosus s. l. genotypes. Also, we report new E. granulosus s. l. samples from Argentina andUruguay analysed by sequencing of cox1 gene.results In South America, five countries have cystic echinococcosis cases for which sequencing dataare available: Argentina, Brazil, Chile, Peru and Uruguay, adding up 1534 cases. E. granulosus s. s.(G1) accounts for most of the global burden of human and livestock cases. Also, E. canadensis (G6)plays a significant role in human cystic echinococcosis. Likewise, worldwide analysis of human casesshowed that 72.9% are caused by E. granulosus s. s. (G1) and 12.2% and 9.6% by E. canadensis G6and G7, respectively.conclusions E. granulosus s. s. (G1) accounts for most of the global burden followed byE. canadensis (G6 and G7) in South America and worldwide. This information should be taken intoaccount to suit local cystic echinococcosis control and prevention programmes according to eachmolecular epidemiological situation.