CESIMAR - CENPAT   25625
CENTRO PARA EL ESTUDIO DE SISTEMAS MARINOS
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Commercial and extracted sodium alginate analysis after purification for bone tissue engineering application
Autor/es:
FERNANDEZ JM; OBERTI T; TORRES ML; CORTIZO AM; DELLATORRE FG
Lugar:
Mar del Plata
Reunión:
Congreso; LXI reunión anual de la sociedad argentina de investigación clínica (SAIC), LXIV reunión anual de la sociedad argentina de inmunología (SAI); 2016
Resumen:
Alginate (Alg) is a natural, water-soluble, polysaccharide obtained from brown algae consisting of β-D-mannuronate(M) and α-L- guluronate(G) residues (1→4). Due to many attractive features such as good biocompatibility, low toxicity as well as ease of hydrogel formation with divalent cations, it has been widely used in a variety of biomedical application, such as medical delivery and tissue engineering. These applications required highly purified materials. However the Alg extracted from brown seaweed and commercial Alg contain a large number of impurities, such as proteins and polyphenols, which might lead to an intense host immune reaction and reduce the biocompatibility of Alg.