congresos y reuniones científicas
CONSOLIDATION OF HUMAN DECLARATIVE MEMORY: AN ALL-OR-NOTHING PROCESS? PRELIMINARY RESULTS
BONILLA MATÍAS; MOYANO MALEN D; KACZER LAURA; BRUSCO IGNACIO; FORCATO CECILIA
Congreso; XXXIV Reunión Anual SAN 2019; 2019
After their acquisition, the new memories go through a lability period in which they become susceptible to the action of either amnesic or facilitators agents. This susceptibility decreases over time and implies a stabilization process known as consolidation. Thus, after learning, the existence of a temporary window is evidenced in which memory is sensitive to interference and, once this period is over, it can no longer be modified. However, spontaneous waves of destabilization have been observed (without the re-exposure to keys linked to learning) in which memory is again sensitive to interference. In the present study we investigate whether declarative memories in humans suffer spontaneous labilizations/re-stabilizations after learning or if they only pass through a single time window, after acquisition, sensitive to interference. Participants learned a list of five pairs of non-sense syllables on day 1. Immediately after, 30 min or 3 hours later they received an interference list that acted as an amnesic agent. They were finally tested on day 3. We also run two control groups that were only trained and tested in one of the tasks. The memory was impaired by the second list only when the interference task was presented immediately after or 3 hours after learning. When the second list was presented 30 min after learning the memory was protected against interference.