Pre-pro-somatostatin-III may have cortistatin-like functions in fish.

CANOSA LF; PETER RE

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.

Año: 2005 vol. 1040 p. 253 - 257

0077-8923

This study analyzes daily changes in the expression of somatostatin precursors PSS-I and PSS-III (structurally related to cortistatin) in the goldfish brain. The results indicate that PSS-I expression correlates with the light cycle only in optic tectum–thalamus (OT-Tha). PSS-III expression correlates with the light cycle in telencephalon–preoptic area (Tel-POA) and OT-Tha. In Tel-POA, PSS-III reaches a minimum level at the beginning of the active phase and a maximum level late in this phase. These results suggest that PSS-I in OTTha and PSS-III in Tel-POA and OT-Tha could be involved in the control of the activity cycles in goldfish